7AAD

7AAD is a red fluorescent vital stain. Dead cells, and membrane-compromised cells stain red. It may be used to Distinguish apoptotic cells from necrotic cells

The use of 7-amino-actinomycin D in the analysis of Candida albicans phagocytosis and opsonization

Kovalev AE, Iakovenko AA, Vekshin NL.
[A study of interaction of 7-aminoactinomycin D with DNA by fluorescence correlation spectroscopy]
Biofizika. 2004 Nov-Dec;49(6):1030-7. Russian.
PMID: 15612543
2: Gaforio JJ, Serrano MJ, Algarra I, Ortega E, Alvarez de Cienfuegos G.
Phagocytosis of apoptotic cells assessed by flow cytometry using 7-Aminoactinomycin D.
Cytometry. 2002 Sep 1;49(1):8-11.
PMID: 12210605
3: Lecoeur H, de Oliveira-Pinto LM, Gougeon ML.
Multiparametric flow cytometric analysis of biochemical and functional events associated with apoptosis and oncosis using the 7-aminoactinomycin D assay.
J Immunol Methods. 2002 Jul 1;265(1-2):81-96. Review.
PMID: 12072180
4: Linden E, Skoglund P, Rundquist I.
Accessibility of 7-aminoactinomycin D to lymphocyte nuclei after paraformaldehyde fixation.
Cytometry. 1997 Jan 1;27(1):92-5.
PMID: 9000590
5: Loborg H, Linden E, Lonn A, Skoglund P, Rundquist I.
High affinity binding of 7-aminoactinomycin D and 4',6-diamidino-2-phenylindole to human neutrophilic granulocytes and lymphocytes.
Cytometry. 1995 Aug 1;20(4):296-306.
PMID: 7587717
6: Rundquist I.
Equilibrium binding of DAPI and 7-aminoactinomycin D to chromatin of cultured cells.
Cytometry. 1993;14(6):610-7.
PMID: 8404367
7: Stokke T, Holte H, Smeland EB, Lie SO, Steen HB.
Differential chromatin structure-dependent binding of 7-aminoactinomycin D in normal and malignant bone marrow hematopoietic cells.
Cancer Res. 1992 Sep 15;52(18):5007-12.
PMID: 1516056
8: Wadkins RM, Jovin TM.
Actinomycin D and 7-aminoactinomycin D binding to single-stranded DNA.
Biochemistry. 1991 Oct 1;30(39):9469-78.
PMID: 1892847
9: Stokke T, Holte H, Steen HB.
In vitro and in vivo activation of B-lymphocytes: a flow cytometric study of chromatin structure employing 7-aminoactinomycin D.
Cancer Res. 1988 Dec 1;48(23):6708-14.
PMID: 3263191
10: Poletaev AI, Stepanova NG, Nikitin SM.
[Effect of deproteinization on the in situ chromatin staining with 7-aminoactinomycin D]
Mol Biol (Mosk). 1988 Jul-Aug;22(4):1062-71. Russian.
PMID: 2460738
11: Stokke T, Steen HB.
Distinction of leucocyte classes based on chromatin-structure-dependent DNA-binding of 7-aminoactinomycin D.
Cytometry. 1987 Nov;8(6):576-83.
PMID: 2448092
12: Uezu E, Takada Y, Mishima N.
Reversible depression of spontaneous brain electrical activity induced by actinomycin D and 7-aminoactinomycin D in rats.
Experientia. 1982 Dec 15;38(12):1446-7.
PMID: 7151959
13: Madhavarao MS, Chaykovsky M, Sengupta SK.
N7-Substituted 7-aminoactinomycin D analogues. Synthesis and biological properties.
J Med Chem. 1978 Sep;21(9):958-61.
PMID: 722760

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